IBM doesn't support the manageprofiles (Profile Management) GUI or wizard in 64-bit operating systems but recently IBM has posted "Manage Profiles Interactive" tool to simplify profile creation process in 64-bit operating systems.
You can download the manageprofilesInteractive.zip from the following link (it also has flash demonstration on how to execute it)
- Extract manageprofilesInteractive.zip to /AppServer/bin
- Execute the command "WebSphere\AppServer\bin>run_manageprofilesInteractive.bat"
- It created the "AppSrv01" profile successfully.